What is Epistane?

Epistane or Methylepitiostanol is a prohormone. It resembles the dihydrotestosterone (DHT), which is a male sex hormone said to slow down baldness. Bodybuilders just refer to this non-progestanic substance as “Epi.” It works by binding itself to the androgen receptors in the cells found in your muscles. After enhancing levels of protein and nitrogen, it will help build muscle mass and boost your strength. Epistane does not aromatize, which means it won’t convert the testosterone into estrogen that can lead to bloating, water retention and fat gain.

Epistane went on the market under the name methepistiostane and launched as an effective drug against breast cancer. As always with prohormones, bodybuilders recognized its benefits due to an 1100:91 ratio of anabolic to androgenic. However, only from the mid-2000s Epistane became a supplement for bodybuilders.

How does Epistane work?

Epistane will make sure your muscle mass can still be retained even if you diet. This is ideal for cutting because only the fat will be burned to augment the caloric deficit.

For newbies, we recommend you take just 30mg daily. For capsules with 10mg and average half-life, it means you have to take it three times every seven hours. The first capsule is taken upon waking up. You should also ingest a pill an hour before working out. You do this for the next four weeks. For those with experience, they can increase the dosage to 40mg daily.

Implement a post cycle therapy (PCT) immediately after taking Epistane. PCT is crucial for your body to produce natural hormones again because they were mangled while you were on Epistane. You really don’t want to develop gynecomastia (female breast development) because you fail to monitor your intake. The rule of thumb is the longer the cycle and the higher the dosage, the bigger the risk of developing gyno. You can minimize the risk by turning back down the amount of milligrams near the end of the cycle.

Benefits of Epistane

Some of the benefits of taking Epistane are:

  • Quick gaining of dry and lean muscles
  • Enhances strength levels allowing you to lift heavier weights
  • Boosts energy levels allowing you to perform more repetitions
  • Helps prevent unwanted fat
  • Little or no water retention

Side effects of Epistane

Epistane is a mild hormone. This means it doesn’t put as much burden on your liver compared to the other prohormones. Unlike steroids that can be very hard for the liver to break down, Epistane contains milder substances. So you are sure that the liver does not actually take a beating when you take it in.

Among the things you should look out for are the negative effects to your blood pressure, good cholesterol and lipids. Further, users sometimes complain about joint pains or lethargy. You may also experience declining sex drive, as well as hair loss. If you cycle at high doses, you will experience dry joints. You can offset this by taking the proper supplements. One of the reasons why this prohormone remains popular is because of its mild side effects. It is unlikely for you to have any acne outbreaks and you won’t be as aggressive. The hair loss is not reported by the majority of users.

Epistane does not come along with many negative side effects unlike its other prohormone counterparts. Thus, you will not experience breakouts or a sudden rise of your blood pressure. When taken in mild dosages, Epistane is completely safe and effective. No wonder that Epi is one of the most popular supplements today in the fitness community in terms of getting the best hard look. Especially for those preparing for a competition.

At low dosages of 30-40mg in a span of three or four weeks, you should be okay. The key, therefore, is to never to abuse the drug by not taking them in high dosages.

Like with any prohormones, we advise to only use Epistane after approval of your medical advisor.


If you are new to bodybuilding and muscle gain, Epistane is ideal for you. This is because its low level of toxicity means you can stack Epistane with other prohormones. Not to mention that it is safe to use. Furthermore, it is also very flexible in the sense that you can use it for quickly gaining solid mass or for cutting. All of this depending on how you stack and cycle.

Our selection of the highest quality Epistane: